BPS 1101 Lecture Notes - Blood Vessel, Atorvastatin, Enalapril
6 Mar 2013
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1st learned from gladiators (anatomy of cardiovascular system from death from fights) William harvey 1600"s considered 1st to figure out the heart (though in reality, it was the egyptians) Diet (weight puts strain on heart salt increases blood pressure) Lack of exercise (exercise increases blood vessels to the heart) Being male (10 times increased risk but after menopause, risk in females = risk in males) Homocysteine --------- methionine [taking more vitaminb will not help[ Ldl often sends cholesterol to blood vessel wall oxidized to cholestenone attracts macrophages inflammation burst which leads to block (increased c-reactive proteins increases risk) Cholesterol made in liver from saturated fats. Omega-3"s are good but only epa and dpa. Statins are inhibitors of hmg coa reductase (part of the pathway that makes cholesterol in the body) Main one used is lipitor by pfizer (#1 drug)
