PSYC 342 Lecture Notes - Lecture 6: Cell Migration, Immunoassay, Radioimmunoassay
Document Summary
Estrogen and the aging brain: more lost more hippocampus volume early in life compared to women, but at old age, they are near- ly the same (due to menopause?) Progesterone receptors in the brain: hypothalamus, median eminence, amygdala, pituitary gland, role in female and male sexual behaviours, in females often in conjunction with estrogen. Hormonal effects on neuronal activation: genomic effects are not instantaneous, non-genomic effects of certain hormones, example: shifting the resting potential of cells in the hippocampus after injection of glucocorticoids. Ablation and replacement: ablation (removal or extirpation) of suspected hormone source, observation of effects, reimplantation of hormone source, observation of (reversed) effects. Berthold"s first experiment in roosters (1849): concluded that based on the behaviour of the rooster, testes were vital to male behaviours (used observations) Behavioural bioassays: the test of the effects of a hormone on the behaviour of a living being, or part of a living being.