Midterm exam: monday march 8th, 6:30pm-8:00pm (30 mc, 30%) Endocrinology is self attenuating (eg: negative feedback loops). The essence of endocrinology: it"s all about communication. In a living organism there must be coordination of number of physiological activities taking place simultaneously such as: movement, respiration, circulation, digestion, excretion and metabolism. Endocrine system and nervous system both signal anatomical parts of the body. The central nervous system and the endocrine system represent the two major means by which these functions are coordinated. Communication between cells that are not in contact is achieved through a number of chemical substances (hormones), which are secreted by releasing cells and interact with specific receptors on distant target cells (bind to them). Signaling through these receptors leads to a specific physiological effect. Cells of the immune system release factors that act in a hormonal way (eg: cytokines). Therefore what we learn about endocrinology can apply to other parts of the body as well!