BIOB11H3 Lecture Notes - Lecture 3: Microtubule, Restriction Enzyme, Escherichia Coli
15 Mar 2013
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Document Summary
Biob11- lecture 3- genome evolution and introduction to the central dogma of molecular genetics. Things that can happen - during unequal crossing over. Fuzzy chromosome image same chromosome but one has suffered an inversion. Some cancers are due to inversions etc. on a chromosome. Transposition means change of position from one place to another. Barbara mcclintock: controlling elements of maize (corn) nobel prize in 1983. A transposable element is inserted into the color gene at make it a colorless kernels. If late then some purple some clear (spot) If it is out early in development then mostly purple. Larger sectors due to transposon jump early in development. Transposable elements do not have a goal site, they can jump into a random site (called recipient or target site) The ends of the transposon are comprised of inverted repeats (in red) Inverted repeat the same sequence from 5 to 3 but arranged in a inverted order (flipped horizontally and vertically)
