NEUR 2600 Lecture Notes - Epistasis, Brca1, Epigenetics
Document Summary
A large part of the genome is involved in brain function. There are many brain abnormalities that are due to genetic abnormalities. Genetic engineering is the science of manipulating the genome and it could be recruited for curing brain abnormalities and diseases. Refers to the possession of genes passed from parent to offspring. Refers to environmental possesses that modify the expression of genes - may be passed from parent to offspring. Refers to combined influence of genetic and epigenetic factors. Genotype of a huntington"s disease subject is not always the same as the phenotype - dominant, but may not be expressed for years. The genotype of a tay-sachs subject is not the same as the phenotype - recessive and has no negative effect. First person to have his entire genome described. Alleles - the copies of a gene from each parent. Recessive - an allele that is not expressed.
