BIOL 200 Chapter Notes - Chapter 7: African Clawed Frog, Wee1, Cdc25

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17 Apr 2017
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The last topic introduced the idea that the cell is broken down into several stages, in which particular events must occur. Like all things in bioloy, there was a time when the details of the cell cycle stages were not known to scientists. The first experiments that showed that there was something controlling the progression of the cell cycle involved injection of cytoplasm into the very large cells of frog (xenopus laevis) oocytes. In each case, the cytoplasm from one oocyte that was at one stage of the cell cycle, was injected into another oocyte, as shown in the image below. The active agent is in the cytoplasm of the cell. Control of dna synthesis and mitosis is positive. That is, that the active agent turns on the process in the recipient cell which is capable to respond but had not yet gotten around to initiating the process itself.

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