Biology 2290F/G Lecture Notes - Lecture 11: Myosin Head, Myosin, Atp Hydrolysis
20 Apr 2017
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Cortical: near the corticle, which is near the outside of the cell. Actin is involved in cell shape and movement because it"s in contact with the pm. Section 3: actin filaments: has lots of receptors on it that change the cytoskeleton, impacting the actin cytoskeleton according to signals. Epithelial cells, migrating cells, muscle and non-muscle functions. All of these structures are formed because actin can form networks and bundles: tubulin is a very linear structure, but actin is much more flexible. Vertebrate isoforms 4alpha (muscle), beta and gamma. G-actin (globular) polymerizes into f-actin (filamentous) microfilaments. Different forms of actin: alpha (found in muscles), beta (corticle actin), gamma: different forms have different functions. When actin is translated, it forms g-actin (globular actin), which has 4 domains. It has a 4-leaf clover shape with an atp-binding cleft: has polarity due to the atp cleft.
