HMB200H1 Study Guide - Final Guide: Cholecystokinin, Afterhyperpolarization, Barbiturate

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26 Apr 2017
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Kolb & whishaw 5e: 4. 2-4. 3, 5. 1-5. 3, 6. 1, figures 6. 5 (ach), 6. 6 (gabaa), 6. 8 (da), 6. 9 (5-ht) Problem set pilots to prepare for midterm exam stage two. Tage (cid:1006) does(cid:374)(cid:859)t (cid:396)e(cid:395)ui(cid:396)e p(cid:396)epa(cid:396)atio(cid:374), si(cid:373)pl(cid:455) a (cid:449)a(cid:455) of (cid:396)e(cid:448)isiti(cid:374)g ha(cid:396)de(cid:396) questions on the midterm and answer them in groups to increase test scores (using scratch cards) Imagine a neuron at rest, with na+ channels open. At equilibrium, the membrane potential will sit at +55mv (equilibrium potential for na+) Electrical gradient and concentration gradients will equally oppose one another. Co(cid:374)(cid:272)e(cid:374)t(cid:396)atio(cid:374) g(cid:396)adie(cid:374)t does(cid:374)(cid:859)t (cid:272)ha(cid:374)ge i(cid:374) li(cid:448)i(cid:374)g (cid:272)ells: equilibrium occurs when na+ channels remain open. At equilibrium, net movement = 0, and concentration gradient = voltage gradient. The(cid:396)efo(cid:396)e, the ele(cid:272)t(cid:396)i(cid:272)al fo(cid:396)(cid:272)e (cid:373)ust (cid:396)e(cid:448)e(cid:396)se, si(cid:374)(cid:272)e the (cid:272)o(cid:374)(cid:272)e(cid:374)t(cid:396)atio(cid:374) g(cid:396)adie(cid:374)ts do(cid:374)(cid:859)t (cid:272)ha(cid:374)ge. In the beginning, the electrical force was inwards. As na+ entered the cell, it eventually reversed and was pointing outwards: when inside of the cell became positive.

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