HK 2810 Study Guide - Final Guide: Positive Feedback, Homeostasis, Snorkeling

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Hk 3940 final exam prep: what is the functional significance of local vs. central regulation? (3 examples) Brain and spinal cord (cns) monitor the interaction of our many bodily systems ensuring our overall survival and coordinate the whole body system, however they don"t have the capacity to maintain/monitor everything at all times (too much traffic). At tissue level, estradiol(-), activin(-), inhibin(+) from sertoli cell works on leydig cells to control testosterone release. Lh and fsh from brain (hypothalamus gnrh anterior pituitary lh and fsh) also controls the testosterone release. Chemo rc in stomach senses the low ph and sends signals to chief cells to release pepsinogen which then is converted to pepsin. Also central nervous system sends signals down via vagus nerve to enteric plexus neurons and to chief cells to release pepsinogen. Direct nervous innervation (both pns & sns) controls the cardiac myocyte contraction by dephosphorylation and phosphorylation, respectively.