CHEM669 Lecture Notes - Lecture 7: Haloperidol, Piperidine, Sertraline
2 May 2017
School
Department
Course
Professor
Document Summary
Below are some of the key issues that were covered in lectures during the month of january. Students are encouraged to review the pdf files of the lecture slides, especially the points to ponder. This was an introductory lecture that did not cover a lot of core content. This lecture introduces a number of terms and concepts that will be encountered again and again throughout the course. This was the first of three lectures on common therapeutic targets and molecular scaffolds. Chem 405/669, winter 2017: cardiovascular drugs (hypertension) b-blockers, ace inhibitors (inspired by a snake venom peptide), calcium channel blockers, cholesterol-lowering. Lovastatin atorvastatin (fermentation products fully synthetic compounds). (hmgcoa drugs reductase inhibitors) compactin: tranquilizers/sedatives barbiturates, benzodiazepines; wakefulness medications (suvoexant, modafinil), antipsychotics chlorpromazine, haloperidol, clozapine, etc, selective serotonin reuptake inhibitors fluoxetine, sertraline, etc. This was a continuation of the targets and scaffolds story.
