MCDB 423 Lecture Notes - Lecture 24: Tsc2, Phospholipid, Tsc1

• School: U of M
• Department: Molecular, Cellular and Developmental Biology
• Course: MCDB 423
• Professor: John Kuwada

Document Summary

When you delete the nogo receptors, the axons do grow a little past the injury site. Answer c was the biggest factor in choosing these genes. All these genes are tumor suppressors so they normally restrain growth. These cells don"t die because the flox system is removing them only from certain cells. So the animal will have gone through devleopment normally slide 6. The cre is introduced to the adult mice using a virus into the eye. Ctb is used only for labeling of the axons. This is a control to see if the method works. This is a reporter to see if the cre is working slide 8. The gfp virus is basically the (cid:449)ild type (cid:272)o(cid:374)trol (cid:271)e(cid:272)ause this (cid:448)irus dna (cid:449)o(cid:374)"t do a(cid:374)ythi(cid:374)g. In the mutant, you see many axons past the injury sites. They noted some fiber in the optic chiasm, but there is no data for as far out as the.