MICR 2420 Lecture 3: Lecture 3_Bacteria
12 May 2017
School
Department
Course
Professor
Document Summary
Why is microbiology important: beer, wine, cheese, yogurt, tabasco sauce, and other fermented foods, agriculture, medicine, biotechnology, astrobiology. Build-a-bacterial-cell workshop: outer membrane option: gram negative, what you get, dna, ribosomes, cytoplasm, plasma membrane, thin cell wall (1 or 2 sheets of peptidoglycan, outer membrane (contains lipopolysaccharide, there are antigens sticking out of the cell. Same shapes as gram positive: available in gram stained red, do not stain violet since there is not enough peptide. Cons: toxic if not handled correctly, requires a bigger genome to make the more complex cell wall - can be expensive to maintain. Gram negative models: e-coli is a standard microbe used in labs, causes cancer by interacting with host cells. Some strains of helicobacter pylori cause stomach ulcers. Is the first microbe listed as a carcinogen. Fresh cultures must be used since they lose their ability to maintain the stain.
