BIOG 1440 Lecture 22: Synapses

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If it"s a sensory neuron: incoming sensory input. Otherwise signals come from other neurons via synapses. Synapses are connections that pass info between neurons. A synapse can form between a neuronal cell and a non-neuronal as well as two neuronal. Neurons can receive thousands to hundreds of thousands of individual synaptic input (pass on just as many) A synapse is a choice point: signal can be passed, withheld, strengthened or weakened. The vast number of synapses between neurons exponentially increases information storage capacity. Synapses allow for remodeling of information flow. New synapses can form between previously unconnected cells. Connexon: like a toothpick through two pieces of bread. Fast and efficient but less ability to transform information. Ap travels down axon and reaches presynaptic terminal. Ap opens voltage gated channel, allowing calcium flow into presynaptic terminal. Ca is good because cell keeps [ca] within the cell very low. Transmitter is released from presynaptic cell when ca signal triggers vesicular exocytosis.

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