BIOL 1000 Lecture Notes - Lecture 21: Pepsin, Enzyme, Cellular Respiration

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Lomoar cpsd| 987298: the enzyme releases the products and emerges unchanged from the reaction . For every enzyme, there are optimal conditions under which it is most effective (e. g. temperature) o. Enzyme"s optimal temperature produces highest rate of contact between reactant molecules and enzyme"s activation site: higher temperatures denature the enzyme (change shape & destroys function) Most human enzymes work best at 35-40 degrees celsius. Close to normal body temperature of 37 degrees . Thermophilic bacteria contain enzymes with optimal temperatures of 77 degrees celsius. Optimal ph for enzymes is near neutrality (6-8) . Exceptions: pepsin works best as ph of 2. Cofactors = non-protein helpers that bind to active site of an enzyme and function in catalysis . Coenzyme = name for cofactor when it is an organic molecule . Many vitamins function as coenzymes or as raw materials that make coenzymes. Folic acid is a coenzyme for many enzymes involved in synthesis of nucleic acids.

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