BIOLOGY 1M03 Lecture Notes - Lecture 4: Sebaceous Cyst, Allele Frequency, Ectopic Expression
15 May 2017
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Document Summary
An identical or almost identical system is used by all known organisms to store the sequences of amino acids. If you incorporate insertions and deletions they differ by ~6% Chimps and humans differ by only ~1. 5% of shared nucleotides. Variation in gene regulation is what led to the differences between humans and chimps. Differences in splicing and regulation led to evolution and differences. Genes are usually named after the mutant genotype. Eyeless is a version in fruit flies and the same mutant/genotype is called pax 6 in humans. Eyeless and aniridua influence where eyes are located in fruit flies and humans respectively. Presumably both are derived from an ancestral gene with the same function" even though the eyes of humans and fruit flies are so different. Ectopic expression is artificial expression in a place where it is not supposed to be expressed in. Functions of genes can be moved and still have the same effect.
