Kinesiology 1080A/B Study Guide - Final Guide: Visual Cortex, Visual Memory, Motor Learning

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Marchi et al. (2013) consequences of repeated blood brain barrier disruption in football players. Watched 5 footballs teams and measured total number of heads hits for the duration of a season. None of the players had a concussion but all had head hits. They measured the level of a protein, s100b. When hit, the protein leaves the blood brain. Barrier causing an immune response and can lead to a cognitive problem in the brain. Blood-brain barrier disruption from sub-concussion leads to surge of s100b protein and an adverse immune response in the brain. Individuals with increased s100b levels showed structural changes via diffusion tensor imagery. Used diffusion tension imagery (dti) to look at brain structure. Measures level of axon connectivity in the brain. How different parts of the pain are connected to other parts of the brain. Individuals with head hits, they have a decrease in axon connectivity during the season, but also before and after head hits.

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