HLTB21H3 Lecture Notes - Subacute Sclerosing Panencephalitis, Oral Rehydration Therapy, Measles Virus
Document Summary
Hard measles: rubella (german measles) , roseola. Sufficient population sizes to support measles did not exist prior to. 2500 bc: no record before that, cannot exist due to small population sizes. Confused with smallpox and other rash diseases for much of history. Rhazes differentiated between measles and smallpox in 910 ad: smallpox and measles were confused even though it looks different, there are variability of diseases that are often confused in the pass. 1846- the faroe island is easy for him to study: there are around 8000 people. Virgin population for 65 years no immunity: anybody who became in contact with these people will be susceptible to the disease. Visits from mainland were rare and well documented: because it was really rare. Epidemic originated with a single arriving sailor. 4 key facts: rash appears 12-14 days after contact with infected person, infectivity greatest 3-4 days before rash appears, respiratory transmission, life-long immunity.
