Biology 1002B Lecture Notes - Lecture 7: Hexokinase, Citric Acid Cycle, Nadh Dehydrogenase

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Next class bring paper and pen, drawing lots of stuff. Convert c-h bonds into atp: carbs, fats, proteins . Glucose uses the entire cellular respiration pathway: need to know where atp is made, where nadh is made. We start with carbon, where does it end up: compare with photosynthesis. The differences, where they occur, how is calvin cycle similar and different than. Glycolysis: splitting of glucose, occurs in the cytosol in eukaryotic and prokaryotes. Energy coupling: glucose catalyzed by hexokinase, not spontaneous, cannot happen by itself, half reactions. Pi + glucose -> glucose 6 p delta g = + 3. 3 kj/mol. Atp + h2o -> adp + pi delta g = - 7. 3 kcal/mol: coupled reaction: Atp + glucose -> adp + glucose 6 p delta g = -4 kcal/mol: water cannot access the active site. A phosphate group is charged, glucose is not charged, so when we add an charge, we can keep the glucose in the same compartment.

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