Biology 1002B Lecture Notes - Lecture 14: Start Codon, Lac Operon, Alternative Splicing
15 Apr 2013
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Document Summary
Eukaryotes can keep the ribosomes away from the mrna just been translated from the nucleus because of the nuclear membrane. Clicker question: the synthesis and function of a typical trna molecule requires complimentary base- pairing with: Does not pair with amino acids, cannot pair, not bases. Operons bring several genes the control of one promoter. Every protein has a stop codon i. e. lac i, lac x, lac y, lac z. Keeping mrna away from the ribosomes are very important: prokaryotes cannot do that. Regulation of transcription initiation: posttranscriptional regulation, translational regulation, posttranslational regulation. Rna polymerase ii does not bind to naked promoters: more than one polymerase in eukaryotes, polymerase ii transcribes protein genes (pcg) Only find promoters attractive when they have protein on the gene: they need the tata promoter. Transcription factors regulate efficiency of polymerase binding. Helix-turn-helix dna binding motif: proteins are not making covalent bonds with dna, lac repressor is a helix turn helix.
