NURS 2090 Lecture Notes - Ibuprofen, Small Intestine, Synovectomy

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Inflammation and tissue repair: vascular response- increase blood flow to the site, cellular response- increase healing cells at the site, repair- prepare for tissue repair (remove injured tissue) Areas not covered by skin are covered by chemically coated mucous membranes that neutralize/ destroy invaders. Specific defense: vascular response to injury (increase in blood flow, facilitated by chemical mediators, acute inflammation is triggered by tissue injury (damage = alteration to cells and tissues- Increased capillary permeability/ bm loosens to allow cells to injured tissue invasion by microorganisms, cellular mutations, hypoxia, nutritional deficiencies, physical or chemical damage) Increased bf needed: phagocytosis/ promote healing, dilute harmful substances. Response at the blood vessel near the site of injury; blood vessels dilate or widen to accommodate increased blood flow to the site; The lining of the blood vessel is more permeable to allow cells to move from the vessel into the injured tissues.

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