MIMM 465 Lecture Notes - Lecture 6: Entamoeba, Syncytium, Common Cold
16 Apr 2013
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Document Summary
Rotavirus major cause of viral diarrhea in young children (also high mortality) Norovirus major cause of viral diarrhea in all ages. Gastroenteritis: an acute infectious syndrome of the stomach lining and the intestine. Syndromes: diarrhea, vomiting, abdominal pain, nausea, fever and chills. Bacteria e. coli, salmonella, shigella and cholera. Parasites giardia lamblia, entamoeba histolytica and cryptosporidium. Gastroenteritis is triggered either by: toxins that are secreted by microbes and lead to excessive loss of water and electrolytes or, by direct invasion of the wall of the gut by microbes, followed by inflammation. >2 million deaths annually, second only to pneumonia for children under 5 yrs of age. 1 in 200 children who contract diarrhea die from it = high mortality in children. 4,500 children die of diarrhea every day in low-income countries. Rotavirus (860,000) > typhoid (600,000) > shigella (600,000) > etec (380,000) > cholera (120,000) Total deaths: 2. 5 million (mostly in young children)
