Microbiology and Immunology 2500A/B Study Guide - Midterm Guide: Septicemic Plague, Phagocytosis, Intracellular Parasite
19 Apr 2013
School
Department
Professor
Document Summary
Evolved from y. pseudotuberculosis transmission for human disease: flea-bite. Handling infected animals (skin contact, scratch, bite) inhalation from humans (pneumonic) or animals ingesting infected meat. Causes yersiniosis a rare cause of diarrhea and abdominal pain. Black death (second pandemic) third pandemic (rodents and fleas) More drug resistant (due to the van genes) Now causes many infections including pneumonia, uti, bacteremia, sepsis important cause of nosocomial pneumonia: faecalis, faecium. Cause urinary tract infections, endocarditis, surgical infections/wounds. Produces a capsule & resistant to many antibiotics. Non-motile, rod shaped, obligate aerobe: bovis, avium, leprae. Staphylococcus epidermidis humans intracellular pathogen (lives within macrophages) Have high concentrations of mycolic acid in the cell envelope. Can cause a tuberculosis-like illness in humans, particularly in aids patients. Surface proteins bind host proteins using adhesins. Pyogenic or pus- producing infection (abscess) resistance to phagocytosis (reorients antibodies) Known for forming biofilms (complex structured communities of bacteria)
