PSYC12H3 Lecture Notes - Heterotrimeric G Protein, Deoxyribonuclease, Receptor Tyrosine Kinase
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E is correct, because stp depends on receptor type, and the integration of all positive and negative signals for a given cell (refer. Which of the following statements is true in regards to receptor protein-tyrosine kinases and the mitogen activated. Raf, mek, erk, and mkp all undergo phosphorylation throughout the cascade. Grb2 acts as an adapter on ras-gdp to convert the molecule into its active ras-gtp form. Once activated, mapk translocates into nucleus where it phosphorylates map kinase phosphatase, facilitating cell proliferation. Without the presence of a receptor, the map kinase cascade can still progress as long as there is a growth factor (ligand) present. Although all 4 molecules have to do with the cascade and rtks, only raf, mek, and erk are actually phosphorylated by mapkk, mapkk, and mapk. Mkp does the opposite to this and removes phosphate groups off of. Mapk to terminate the signal (riggs, lecture 24, slides 6-7: false.
