BIOC 300A- Midterm Exam Guide - Comprehensive Notes for the exam ( 39 pages long!)

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Biochemistry the branch of science that seeks to explain biological form and function in chemical terms. Bonding geometry (b) single bonding rotatable & flexible (c) double bond rigid. Peptides some bonds maybe rotatable while others are not, meaning they consisting of single, double or triple bonds. Folding w/o any double bonds = hard because of randomness & enthalpy penalty. Double bonds give a pre-exiting rigid structure lowering the enthalpy penalty & making folding easier (other components in folding like nc bonding) Noncovalent bonds (nc bonds) major contributor to stability in biological systems oppositely charged group on the same or another molecule. atoms attracting one another. Create double helix in dna an atom fluctuates with time. At any instant, the charge distribution is not perfectly symmetric. Covalent bonds formed by sharing a pair of electrons between two adjacent atoms (can be more than one pair). A lot of energy needed to break them.

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