BISC403- Midterm Exam Guide - Comprehensive Notes for the exam ( 45 pages long!)

• School: University of Delaware
• Department: Biological Sciences
• Course: BISC403
• Professor: Olabisi Oyenike

Document Summary

Lecture xi chapter 8, gene expression: the flow of information from dna to rna to. Four general themes for gene expression a molecular assembly line: complementary base pairing is the key to the transfer of information from dna to. Rna and from rna to protein: polarities of dna, rna, and polypeptides help guide the mechanisms of gene expression b. i. Gene expression: flow of genetic information from dna via rna to protein: rna polymerase transcribes dna to produce rna transcript, ribosomes translate the mrna sequence to synthesize a polypeptide, translation follows the genetic code . Important to know what happens to the polypeptide chain when it goes wrong. Which codons represent which amino acids? a. b. Preparation of cellular extracts that allowed translation in a tube b. ii. Developed techniques to synthesize artificial rna"s with known nucleotide sequence b. iii. Using synthetic mrnas and in vitro translation to crack the genetic code. Genetic code is almost, but not quite, universal a.