HLTB21H3 Lecture 6: lecture 6
Document Summary
Mortality rate is 3% in vaccinated and 30% in unvaccinated. Malignant and hemorrhagic forms develop in ~ 5-10% of infected people -- almost always fatal, 95% mortality rate in malignant. Hemorrhagic smallpox black pox, with extensive bleeding into the skin, mucous membranes, and gastrointestinal tract. Milder disease - mortality rate is ~ 1% in unvaccinated persons. 10 000 bc; first agricultural settlements in ne africa and spread to india through. Egyptian pharaoh ramses v (died 1156 bc) shows to have died of smallpox. Plague of antonine - decline of roman empire @ 108 ad. Fall of spanish/portuguese population and aztec empire. Decline in native population in north america. - 1754-1767 french-indian war -- suggested the deliberate use of smallpox to diminish the american indian population. Orthopoxvirus -- family of poxviridae -- variola virus (also responsible for monkey pox, cowpox, camelpo, chickenpox, and extremely (mouse pox)) Mortality is generally higher when individual is under a year old.
