BIOL311 Lecture Notes - Lecture 3: Gc-Content, Pribnow Box, Nucleobase
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Document Summary
In a dna double helix, each type of nucleobase on one strand bonds with just one type of nucleobase on the other strand. Here, purines form hydrogen bonds to pyrimidines, with adenine bonding only to thymine in two hydrogen bonds, and cytosine bonding only to guanine in three hydrogen bonds. This arrangement of two nucleotides binding together across the double helix is called a base pair. As hydrogen bonds are not covalent, they can be broken and rejoined relatively easily. The two strands of dna in a double helix can therefore be pulled apart like a zipper, either by a mechanical force or high temperature. As a result of this complementarity, all the information in the double-stranded sequence of a dna helix is duplicated on each strand, which is vital in dna replication. Indeed, this reversible and specific interaction between complementary base pairs is critical for all the functions of dna in living organisms.
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Related Questions
Relate the following columns:
A. In the complementary strands of DNA are exposed to the aqueous environment. | ( ) Bridges of H. |
B. They are in the hydrophobic interior of the DNA double helix. | ( ) 2-DNA. |
C. They are van der Waals interactions between pairs of stacked bases. | ( ) Sugar-phosphate skeletons. |
D. They are an important stabilizing force between base pairs. | ( ) Purines and pyrimidines. |
E. It's the approximate conformation found in the cells. | ( ) A-DNA. |
F. It's favored when the DNA is dehydrated: | ( ) Stacking interactions. |
G. It's favored in certain sequences rich in G/C | ( ) B-DNA. |
H. The protein machinery that carries out DNA polymerization. | ( ) Okazaki fragments. |
I. Short fragments of DNA strand. | ( ) DNA Helicase. |
J. Just with DNA-PolIII and other proteins is a part of the replisome. | ( ) Primosome. |
K. Synthesize the RNA primers. | ( ) Primase. |
L. Unroll the two strands of the parent double helix. | ( ) SSB. |
M. It joins the double strand and prevents it from bending back. | ( ) Replisome. |