NURS 203 Lecture Notes - Membranoproliferative Glomerulonephritis, Membranous Glomerulonephritis, Fluorescent Tag
Document Summary
Itis = type iii hpy therefore it"s an immunologic dz (glomerulonephritis) When we say diffuse", this means that every glomerulus has something wrong with it on renal bx. Have a problem this is called focal. If all the glomeruli have a lot of nuclei, this is diffuse proliferative glomerulonephritis. If you just see thick membranes, its membranous glomerulonephritis. The order is: blood, endothelial cells of the capillaries, underneath there is a bm, and then the visceral epithelial cells (looks like feet = podocytes; which have spaces in between them called slit pores) that line the bowman"s capsule. A gag called heparan sulfate, which has a strong neg charge. The bm, which means you"re gonna spill a lot of protein in the urine, which means you potentially can have nephrotic syndrome if you spill >3. 5 grams in. Stains routine h & e hemotoxylin stains, silver stains.
