NURS 287 Lecture Notes - Lecture 15: Transjugular Intrahepatic Portosystemic Shunt, Primary Biliary Cirrhosis, Gastric Varices
28 Apr 2013
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Document Summary
Wilson"s disease is a progressive, familial, terminal neurologic disease accompanied by chronic liver disease leading to cirrhosis. It is associated with increased storage of copper. Primary biliary cirrhosis (pbc) is characterized by generalized pruritus, hepatomegaly, and hyperpigmentation of the skin. Nonalcoholic fatty liver disease (nafld) is a group of disorders that is characterized by hepatic steatosis (accumulation of fat in the liver) that is not associated with other causes such as hepatitis, autoimmune disease, or alcohol. The risk for developing nafld is a major complication of obesity. Nafld should be considered in patients with risk factors such as obesity, diabetes, hypertriglyceridemia, severe weight loss (especially in those whose weight loss was recent), and syndromes associated with insulin resistance. Cirrhosis is a chronic progressive disease characterized by extensive degeneration and destruction of the liver parenchymal cells. Common causes of cirrhosis include alcohol, malnutrition, hepatitis, biliary obstruction, and right-sided heart failure.
