STA220H5 Lecture Notes - Calcitriol, Adipose Tissue, Disulfide
Document Summary
Slide 2- hormones differ by release and feedback of hormone. Slide 3- pancreas is exocrine (pancreatic duct makes and release enzymes, release it back to small intestine and important for digestion) and endocrine (cell makes and releases hormones- not neurosecretory. Good capillary supply in islets (clusters of endocrine cells; when release hormones, it has to go into the bloodstream, so a good capillary system is needed) slide 4- the last two hormones mentioned are very important for digestion. Focusing on first two hormones today (glucagon, insulin) Can have convulsions/ death if too much/ too little glucogon. Excess food and glucose is either stored as glycogen or lipids. We eat, digest, absorb, use some and store rest. Glucagon works on liver tissue slide 5- both are polypeptides. Insulin- 51 aa polypeptide a dimer of an a- chain and b chain held together with disulphide bond. Glucose is only energy brain can use, so control is vital.
