BIO120H1 Lecture Notes - Lecture 9: Tata-Binding Protein, Tata Box, Eukaryote

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28 May 2013
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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Lecture outline: structure of a gene, rna polymerases, transcription of protein-coding genes, rna processing. Gene structure is more complex in eucaryotes. 1 of those things are removal of intron sequences to put together entire coding sequence of protein. Other things that need to happen is putting on of rna cap at 5" end (5" capping) as well as poly-adenylation at 3" end. Then you can have exporting of mature mrna transcript out of nucleus & into cytoplasm where it can then be translated something that doesn"t happen in prokaryotes. This is much different than in prokaryotes which only have direct transcription and translation. Eucaryotes have 3 different kinds of rna polymerases not just. 1 as the 1 found in procaryotic tend to transcribe different sort of genes. Rna polymerase ii transcribes protein coding genes this is the most similar to the polymerase in procaryotes. 5. 8s, 18s are different sizes of the mrna. Svedberg units are the measurement of rna sizes.

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