MGY378H1 Study Guide - Parvovirus, Myc, Provirus
3 Jun 2013
School
Department
Course
Professor
Document Summary
Parvovirus replication help melt ends and bend dna back into t shaped structure. Autonomous part aav parvoviruses inverted terminal repeates sequences same at both ends autonomous parvoviruses each end has unique sequence but sequence at one end isn"t the same as sequence at the other. Gene expression late messengers all come from common promoter big transcript and then splicing to make final mrna, which will have coding sequence for protein three little pieces of. Rna, spliced onto end of each message for getting out of nucleus and getting translated host shut off processes disabled for most mrna. A cell lne has a retorviurs integrated into tis genome which has the following structure. Virus is harvested from teh cells and used to infect a second cell line. A transformed cell line has been isolated. Analysis of gene expression in the cells reveals increased expression of the myc oncogene, further study reveals that the myc rna conatins teh.
