PSYCH 2AP3 Lecture Notes - Dopamine, Prefrontal Cortex, Birth Weight

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Looking for endophenotypes compare full phenotype (full set of symptoms) of the disorder. Advantage: a lot more people to look at. Extraversion: individual whose behaviour is outgoing, leadership, risk-taker, style with which we respond to things sociable associated with the dopamine activity level. Based on dopaminergic circuits: major treatment is to give them stimulants for dopamine. Neuroticism: tendency to experience negative emotions, more reactive to stimuli, thought to involve limbic system, amygdalda. Related to range of psychopathologies conscientiousness: impulsivity, inability to hold back from making decisions. Pre and post natal toxin exposure: mercury, manganese, lead. No clear evidence re psychological factors: low ses: low socio-economic status, poverty and low levels of education. Adhd denotes a grouping of multi factorially determined syndromes without an established causal etiology and with fuzzy boundaries . Neuropsychological models will not explain adhd all by themselves multiple developmental pathways no doubt exist for children with adhd .

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