BIO109 Final: Hematology final outline.docx

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Mccqe 2000 review notes and lecture series: hereditary hemolytic anemia. Low or normal reticulocytes hypochromic microcytic (mean red cell volume mcv < 80) Chronic disease normochromic normocytic (80 < mcv < 100) Primary marrow abnormalities macrocytic/megaloblastic (mcv > 100) megaloblastic b12 macrocytic hypothyroidism. History t bleeding t drugs e. g. asa, nsaids t family history and ethnic background t diet t malabsorption t recent pregnancy. Symptoms t general: fatigue, malaise, weakness t cvs: palpitations, syncope, dyspnea t neurologic: headache, vertigo, tinnitus. Koilonychia (spoon-shaped nails) as in iron deficiency anemia. Dic t wbc and platelet count normal. Focused history, physical exam, cbc, and peripheral blood film (pbf) Iron intake (dietary) t average canadian adult diet = 10-20 mg fe/day t absorption = 5-10% (0. 5-2 mg/day) t fe absorption increases with. Fe depletion t males have a positive fe balance t menstruating females have a negative fe balance.

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