HLSC 2460U Lecture Notes - Tnm Staging System, Neutrophil, Lymph Node
Document Summary
Cancers that started growing from individual cells and eventually turned into a mass. 5-10cm in diameter (later in the process) A fracture/injury would lead a person to seek medical attention. Diagnosed earlier because it is confined by the skull. As the tumor grows, compression will cause symptoms. Atypia; develop into an in-situ neoplasm also called carcinoma (technical name for cancer of epithelial) In-situ neoplasm is composed of cancer cells that have not yet invaded normal tissue. Invasive neoplasm started as in-situ neoplasm/carcinoma but is now invading and destroying normal tissue (submucosa in the gut) All human cancers undergo this spectrum of change, all started from normal tissue dysplasia atypia. Almost all human cancers are diagnosed when they are invasive (except we can sometimes catch breast cancer at in-situ stage) Not unusual to see mitosis (high mitotic index) Not a well-defined border because there is a bit of invasion of local tissues.
