PHGY 313 Lecture Notes - Prednisone, Xenotransplantation, Epitope
17 Jul 2013
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Type 1 diabetes: specific destruction of the -cell producing insulin in the islets of langerhans. The -cells present insulin on their cell surface but the t cells recognize it as foreign. Multiple sclerosis: most common disorder of the cns, mediated by t cells where there"s an immune response against your neurons via several brain antigens: Myelin oligodendrocyte glycoprotein: the pathological trigger is still largely unknown. Once triggered however, leukocytes and blood proteins become permeable through the blood brain barrier: one treatment is a stent in the brain, which will remove inflammation. The act of transferring cells, tissues, or whole organs from a different individual: also includes moving your own skin to a different location. A transplanted organ/tissue is called a graft. Your t cells are sensitive to foreign antigen (either foreign. In general, 3 advances have been made that makes transplantation a routine and effective treatment.
