Biology 2382B Lecture Notes - Microtubule, Stokes Shift, Vacuole
24 Aug 2013
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Document Summary
Anton van leeuwenhoek was the first person to construct a microscope adequate enough to observe live cells, back when people didn"t even know cells existed. His microscope was simplistic, but shares many features of modern microscopes. He would set drop of cell culture on the pin of the microscope and examine live cells in sunlight by moving the stage closer or further away from view. Leeuwenhoek"s success at protozoa and bacteria ( animalcules ) as well as erythrocytes and sperm cells was due to his skill at grinding lenses (maximizing the lens" magnification and resolution) and his naturally acute eyesight (achieving a total magnification of 200x). As opposed to leeuwenhoek"s single lens microscope, a compound microscope is a light microscope using two or more lenses (increasing the magnification properties). The condenser helps to focus the light from the light source on to a specimen, which is usually mounted on a glass coverslip or microscope slide.
