PSYB32H3 Chapter Notes -Naltrexone, Grey Matter, Network Theory
Document Summary
2 categories: substance abuse and substance dependence. At least 3 of the following: person develops tolerance: a) larger doses for desired effect b) effects less if usual amount taken. Dsm 5: pathological gambling be included, inclusion of behavioural addictions. Substance abuse diagnosed as accompanied by physiological dependence. One of the following: failure to fulfil major obligations, exposure to physical damages, legal problems, persistent social or interpersonal problems. Substance intoxication ingestion of substance affects the cns. Dts/delirium tremens substance withdrawal from alcohol. Dsm-5: quantitative severity distinction rather than qualitative b/w substance abuse and dependence; so include both disorders together: substance use disorder symptoms less useful for severe/mild pathology. Alcohol dependence tolerance or withdrawal, those who drink early have issues in 30-40"s. Increased tolerance following heavy drinking: body adapts to drug and can process more effectively, tolerance results from changes in number/sensitivity of gaba or glutamate receptors, when drinking stops, receptors overactive.
