Biology 1001A Lecture Notes - Lysis, Integrase, Sub-Saharan Africa
4 Sep 2013
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Associated reading: p. 491-493, look up different hiv inhibitors (see slide 13) September 12, 2012 total 33. 3 million people estimated to be living with hiv or aids. Has a dramatic effect on the quality of life / lifespan of heavily affected areas. About 60% of those affected live in sub-saharan africa. Hiv is a virus and embeds itself in host dna. This makes it difficult to avoid killing the host cell when attacking the virus. Political issue with funding, not enough profit to be made. People are not willing to participate in clinical trials. Obligate cellular parasites ( require host cell & organelles to reproduce) Anti-viral therapy has serious side effects as viral rna becomes embedded into dna. Not on the phylogeny of life b/c viruses are non-living, contained in the. Starts in rna form and goes through reverse transcription (reverse transcriptase) to embed itself in dna to be transcripted, translated into proteins.
