MELS223 Lecture Notes - Lecture 10: Bacteriuria, Drug Resistance, Peripheral Venous Catheter
6 Sep 2013
School
Department
Course
Professor
Document Summary
Infections not0 present and without evidence of incubation at the time of admission to a healthcare setting. Onset 48 hours after admission or within 30 days of discharge. Increasing number of people with compromised immune systems. Pathogenesis of hospital acquired infections chain of infection! Require susceptible host age, underlying disease, drugs, diabetes. Virulent organism antimicrobial resistance (70% of cases) Portal of entry anatomic barriers breached. Uti = most common form of hai. ~100% of patients develop bacteriuria after 30d catheter use. Source or uropathogens: endogenous catheter insertion, retrograde movement up the urethra, patient"s own faecal flora. Growth in biofilm = increased antimicrobial resistance. Onset at least >48 hours after admission. 2nd most common hai (13-18% of all hai) Aetiology : gram negatives from faecal flora (aspiration of gastric contents) Empiric due to risk/potential for resistance to 1st choice drugs. Drugs can be altered once sensitivities determined. Needs to cover pseudomonas, e. coli, klbsiella and mrsa.
