BIOSC 0160 Study Guide - Midterm Guide: Pleiotropy, Richard Dawkins, Genetic Counseling

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13. 1: quantitative, considers pattern in numbers of offspring of crosses, central approach in classical genetics. Useful vocabulary: homozygous: posses two identical alleles, heterozygous: posses two different alleles, phenotype: appearance of organism or cell, genotype: genetic make-up, punnett square. F2 punnett square (shown) genotypic ratios: 1:2:1 (pp : pp : pp) Chapter 11: a crucial result: inheritance is particulate, not blending, if only darwin had known (read mendel"s work but didn"t understand) Human mendelian genetics: pedigree analysis, family tree describing relationships, human disorders as mendelian traits, recessively inherited disorders, e. g. , cystic fibrosis, e. g. , tay-sachs disease. Chapter 11: dominantly inherited disorders, e. g. , huntington"s disease (neuron degenerative disease, carrier recognition: individual not inflicted with disease but carries disease causing allele, genetic counseling and pedigree analysis, direct testing. Mendel and chromosomes: chromosomal theory of inheritance. Linkage: drosophila example, dihybrid: color and wing shape, gray (b+) dominant over black (b, normal (vg+) dominant over vestigial (vg)

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