BIOL 205 Lecture Notes - Lecture 6: Fusion Protein, Sybr Green I, Autoradiograph
27 Sep 2013
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Nov 5/11 lecture 6: good mutations. 10% copies of chemokine receptor #5 in human genome have a deletion due to a frameshift. Having this deletion makes people resistant to hiv. Had 15% more red blood cells than normal which helped him increase o2 capacity by 50% He had a mutation in erythropoietin receptor that cause increased blood production. Mutagenesis: production of mutations in the laboratory through exposure to. A: they"re both thymine dimers but just more specific names based on where the bonds are: testing methods for mutagens mutagens. \ Base analogs: chemical compounds sufficiently similar to normal nitrogen bases of. Dna that they"re occasionally incorporated into dna in place of normal bases. Once in place, these analogs have different pairing properties that causes a wrong nucleotide to be inserted oppositely. Chemicals that resemble normal nitrogen bases get incorporated into dna: ex. 5-bromouracil, normally paired with adenine, it becomes ionized and pairs with guanine instead = transition (a g)
