Biology 1001A Study Guide - Midterm Guide: Dna Polymerase, Single-Nucleotide Polymorphism, Dna Replication

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Hiv: becoming global pandemic, estimated 33 million people affected worldwide, very common in sub sahara africa. How do viruses replicate: adhesion, in ltration of host cell, injection of viral genome, hijacking of host cell machinery to create new viral particles. Retrovirus: hiv is a retro virus, means has a rna genome, rna must be reverse transcribed into dna once in host cell, enzyme reverse transcriptase target for anti viral, azt, inhibits reverse transcriptase . Origins of life: 3 stages of prebiotic evolution. Central dogma: dna rna protein, rna has both information storage ability, and enzymatic activity, dna rna protein (likely started with rna) The genome: the amount of dna in one genome is called c . Circular chromosomes is ancestral: mitochondria and chloroplasts have circular chromosomes, it is thought that the last universal common ancestor had circular chromosomes. Ploidy: number of sets of chromosomes, haploid: one copy, diploid: two copies, triploid: three copies, tetraploid: four copies.