BIOB10H3 Lecture Notes - Lecture 6: Endomembrane System, Phagocytosis, Lysosome
12 Oct 2013
School
Department
Course
Professor
Document Summary
Building lysomes means to target the correct proteins. Endocytosis and phagocytosis brings things in and directs them to the lysosomes: how are proteins sorted with the endomembrane system, sorting signals what is the default" secrection. There are specific proteins that pinch in the membrane and other proteins that direct them where to go. Rabs are proteins that pair this vesical" to its target smares mediate docking and fusion. Specific rabs will direct certain proteins to the member. Three biologists the won the nobel prize for thein work on vesicle trafficking components of plasma membrane lipids, proteins, carbohydrates lipids and proteins can move around or not if they are bound to cytoskeleton. Passive transport no energy going from high to low concentration not agains the concentration gradient ion channels these are transmembrane proteins. Gated need a signal to be in the open or closed configuration ligand binds to channel.
