Biology 1002B Lecture Notes - Electrochemical Gradient, Lipid Bilayer, Alpha Helix
13 Oct 2013
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Membrane protein: have several alpha helices, hydrogen bonding minimizes charges in backbones enabling the protein to interact, the nonpolar amino acids are hydrophobic, the polar and charged amino acids are hydrophilic. Modeling a neuron: ions diffuse along electrochemical gradients (ions have charges) Uses atp energy: moves from higher to lower concentration, k doesnt move to equal concentrations on both sides, charge across a membrane is the inside chamber in relation to the outside. Photoreceptor cell: receptor, receptor cell, rodopsin, dark: glutamate (neural transmitter) is released, electric pulse switches off glutamate which then sets of an electric pulse down the nerve. Cystic fibrosis and cftr: cf caused by mutation to cftr, 6000 bases, 1480 amino acids, most common delta f508 (70% of cases, deleted feloalimine at position 508, delta means deleted. Jan 22, 2013: cilia must be kept wet which cftr is responsible for pumping chloride which pumps.
