KINE 2011 Lecture Notes - Cell Adhesion Molecule, Lipid Bilayer, Cystic Fibrosis
Document Summary
Plasma membrane also known as the cell membrane and surrounds every cell. Separates cell contents from its surroundings (separates icf and ecf: hydrophobic interior serves as a barrier from water soluble substances from entering between ice and ecf. Controls movement of molecules in and out of the cell. The extremely thin layer of lipids and proteins that form outer layer of each cell is needed to: Required for a cell to function normally. Fluid lipid bilayer (phospholipid bilayer) embedded with proteins. Peripheral are only attached to the outside layer of the membrane. Cholesterol, acts as a buffer between phospholipid molecules to maintain fluidity and stability of cell membrane. Attached to or inserted within the lipid bilayer: functions of proteins: Surface proteins important for self-recognition and in cell-cell interactions. Self-identity markers enables cells to identify and interact with each other. May also be involved with tissue growth. Discovered by lap-chee tsui at sick children"s 1989 now head of university in china.