NATS 1670 Final: Passive Immunization Describes advantages and disadvantages, describes vaccines and shows some milestones in active immunization

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16 Oct 2011
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Risk of infection with unknown pathogens ie. in the 80"s hepatitis and aids. Most of the damage to the cells during infections occur very early, often before the clinical symptoms of disease appear. This makes drug treatment of infection irrelevant in many cases. Prevention of infection is better and cheaper. Organisms/ molecules that elicit an immune response. Trigger active immunity, stimulating the body to defend itself. Provide protective immunity against a potential pathogen. Describes a type of immunity, that occurs when the vaccination of a portion of the population provides protection to unprotected individuals. Variolation (inoculation with the wild type smallpox) Edward jenner discovers a safe smallpox vaccine. Exposed a healthy child (his own) to cowpox virus from a milkmaid and then attempted to infect the boy with smallpox virus. Method works because cowpox shares antigens with smallpox, but doesn"t cause the disease. In 1980 the world health organization officially declared the world and its peoples" free from endemic smallpox.

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