NROC69H3 Lecture Notes - Lecture 6: Theta Wave, Schaffer Collateral, Naloxone
Document Summary
Hippocampus: together with the amygdala, the hippocampus is the central component of the limbic system. Hippocampus and cortico-striatal loops: the hippocampus is a major component of the affective" cortico-striatal loop, providing limbic information to both the ventral striatum and medial prefrontal cortex. Hippocampus proper: well defined laminar structure with clear layers made up of rows of pyramidal cells, septotemporal axis, transverse axis. Principal neurons: dentate gyrus, granule cell, unipolar, dendrites emanate upwards, ca3 / ca1 / subiculum, pyramidal neurons, top down, tuft, apical dendrites, soma, basal dendrites. Dendritic length of principal neurons: ca1, pyramidal cell layer, stratum pyramidale, stratum radiatum, stratum oriens, dg area, granule cell layer, molecular layer, polymorphy cell layer (hilus) Synaptic inputs to pyramidal neurons: tuft, excitatory inputs from extrinsic sources, e. g, entorhinal cortex, thalamus, apical and some basal dendrites, excitatory inputs from local sources, e. g, ca3, apical areas, basal dendrites. Inhibitory (gabaergic) inputs from local interneurons: perisomatic areas.
