PSY395H5 Lecture Notes - Lecture 4: Oophorectomy, Miscarriage, Prenatal Diagnosis

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22 Oct 2013
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First fact known removal of ovaries stops mating. Need to know what ovaries do, when they do it: remove ovaries and look at microscopically. Unlike males, most females not always ready to mate. In many rodents, this cycle occurs every few days. In many larger animals, this cycle occurs seasonally: cell types found in vaginal lining vary according to ovarian function. In rats, cell types cycle every 4-5 days: estrus cornified (crunchy) epithelial cells, diestrus mostly leukocytes (white blood cells, proestrus round, nucleated epithelial cells. In primates, called menstrual cycle: moon , not called estrus cycle, because mating (estrus) Not confined to a particular phase: surge of gnrh, surge of estradiol, ovulation, menstruation when estrogen + progesterone lowest, endometrial (outermost) layer of uterus shed, blood vessels near surface now exposed and leak. Estrogen does not induce mating in all females: about 40% of rats/mice do not mate with estrogen alone, progesterone.

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