BI110 Lecture Notes - Lecture 7: Hydrophile, Central Dogma Of Molecular Biology, Thomas Cech
Document Summary
Clicker question answers: organic molecules essential to formation of life could have been made in the absence of life in the conditions on primordial earth, miller-urey experiment showed that molecules crucial to life could be produced abiotically. Miller-urey experiment: ~50% of carbon put into experiment came to be part of organic molecules, their experiment did not produce macromolecules; only the building blocks (purines, pyramidines, fatty acids, etc. ) Protobionts: the first cells: protobionts --> group of abiotically-produced organic molecules surrounded by membrane/membrane-like structure. Phospholipids in a sol"n can spontaneously form a membrane. Phospholipids have hydrophilic heads and hydrophobic tails; hydrophobic tails associate and hydrophilic heads point away from each other thus in a sol"n, they spontaneously arrange into a membrane. Macromolecules captured in the middle of a membrane-bound vesicle. Essential to formation of life; gave a separate environment from aqueous environment. The central dogma: dna --> rna --> protein.
